Correlation of foxl2 with inhibin and calretinin in the diagnosis of ovarian sex cord stromal tumors
نویسندگان
چکیده
منابع مشابه
Correlation of FOXL2 with Inhibin and Calretinin in the Diagnosis of Ovarian Sex Cord Stromal Tumors.
OBJECTIVE Alpha-inhibin and calretinin have been traditionally used as immunomarkers for sex cord stromal tumors. However, the variation in their immunoreactivity and their lack of specificity for sex cord stromal tumor makes the search for a more sensitive and specific immunohistochemical marker essential in routine diagnosis of sex cord stromal tumor. This study was conducted to correlate the...
متن کاملGranulosa Cell – Stromal Tumors: An Immunohistochemical Study Including Comparison of Calretinin and Inhibin
Background and Objective: Histopathological evaluation of granulosa cell tumors (GCT) of the ovary may be confused morphologically with a wide variety of the tumors. Immunohistochemical staining for inhibin and calretinin can be used for better diagnosis. Although it has been suggested that inhibin can be a sensitive marker for GCT, it maybe had negative results in some cases. In addition, cal...
متن کاملGenetics and genomics of ovarian sex cord-stromal tumors.
Ovarian sex cord-stromal tumors (SCST) represent approximately 8% of malignant ovarian tumors. The most common are granulosa cell tumors (GCT) which account for approximately 90% of malignant SCST. Recent studies have unraveled the key genomic and genetic events contributing to their pathogenesis. SCST are found in the hereditary syndromes: Peutz-Jeghers syndrome, Ollier disease and Maffucci sy...
متن کاملgranulosa cell – stromal tumors: an immunohistochemical study including comparison of calretinin and inhibin
background and objective: histopathological evaluation of granulosa cell tumors (gct) of the ovary may be confused morphologically with a wide variety of the tumors. immunohistochemical staining for inhibin and calretinin can be used for better diagnosis. although it has been suggested that inhibin can be a sensitive marker for gct, it maybe had negative results in some cases. in addition, cal...
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ژورنال
عنوان ژورنال: Turkish Journal of Pathology
سال: 2016
ISSN: 1018-5615,1309-5730
DOI: 10.5146/tjpath.2016.01382